Inferences from Genomic Models in Stratified Populations

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Inferences from genomic models in stratified populations.

Unaccounted population stratification can lead to spurious associations in genome-wide association studies (GWAS) and in this context several methods have been proposed to deal with this problem. An alternative line of research uses whole-genome random regression (WGRR) models that fit all markers simultaneously. Important objectives in WGRR studies are to estimate the proportion of variance ac...

متن کامل

Population Genomic Inferences from Sparse High-Throughput Sequencing of Two Populations of Drosophila melanogaster

Short-read sequencing techniques provide the opportunity to capture genome-wide sequence data in a single experiment. A current challenge is to identify questions that shallow-depth genomic data can address successfully and to develop corresponding analytical methods that are statistically sound. Here, we apply the Roche/454 platform to survey natural variation in strains of Drosophila melanoga...

متن کامل

Inferences from Cross-Sectional, Stochastic Frontier Models

Conventional approaches for inference about efficiency in parametric stochastic frontier (PSF) models are based on percentiles of the estimated distribution of the one-sided error term, conditional on the composite error. When used as prediction intervals, coverage is poor when the signal-to-noise ratio is low, but improves slowly as sample size increases. We show that prediction intervals esti...

متن کامل

Polya Posterior Quantile Estimation for Stratified Populations

We develop extensions of the Polya posterior that can be used to estimate population quantiles in stratified populations. In the simple case with no auxiliary information, estimates based on this extension to the Polya posterior perform similarly to the standard frequentist estimates. The Polya posterior can be extended to incorporate a variety of prior knowledge about an auxiliary characterist...

متن کامل

From samples to populations in retinex models

Some spatial color algorithms, such as Brownian Milano retinex (MI-retinex) and random spray retinex (RSR), are based on sampling. In Brownian MI-retinex, memoryless random walks (MRWs) explore the neighborhood of a pixel and are then used to compute its output. Considering the relative redundancy and inefficiency of MRW exploration, the algorithm RSR replaced the walks by samples of points (th...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Genetics

سال: 2012

ISSN: 1943-2631

DOI: 10.1534/genetics.112.141143